eGFR — Revised Schwartz (bedside, paediatric)
Estimates GFR in children aged 1–16 years from height and serum creatinine (revised 'bedside' Schwartz equation, 2009).
Formula
Serum creatinine in mg/dL (divide µmol/L by 88.4 — handled automatically). The constant 0.413 assumes an enzymatic, IDMS-traceable creatinine assay. Full multivariable versions incorporating cystatin C and BUN were published in the same paper.
Caveats & limitations
- Validated in children aged 1–16 years with chronic kidney disease; not validated in neonates, healthy children, or acute kidney injury.
- Less accurate at extremes of muscle mass (e.g. spina bifida, muscular dystrophy) — consider cystatin C.
- Do not use adult equations (CKD-EPI, Cockcroft–Gault) in young children.
Evidence & UK guidance
Primary evidence
Schwartz GJ, Muñoz A, Schneider MF, et al. New equations to estimate GFR in children with CKD. J Am Soc Nephrol. 2009;20(3):629–637.
UK practice
The standard bedside eGFR equation for children in UK paediatric practice. Use enzymatic/IDMS-traceable creatinine; cystatin C–based equations are preferred where available, particularly when muscle mass is atypical.
Official resources
Formula and citations last verified: 2026-08-03